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Expansion of Knowledge Map of Chemical Substances.

Absrtact
We review the assessment mechanisms and standard procedures for chemical substance management in the United States, Canada, EU, Japan and South Korea and screen 30 chemical substances. Assemble and evaluate international screening and screening mechanisms for chemical substances and take into account international regulatory directions such as the use of chemical substances, toxicological information, environmental spread, carcinogenicity, persistence, bioaccumulation and toxicity, and improve the basic information on the management of chemical substances in Taiwan .According to the four basic steps of health risk assessment, a database of the concentration of environmental chemicals in 30 categories of chemical substances has been set up, which includes the identification of chemical substances, the identification of hazards, the assessment of dose effects and the concentrations of local environmental media monitoring concentrations. Results from the risk assessment of dioxin and cadmium show that males and females in all regions of Taiwan, compared with the TDI value recommended by the World Health Organization (1-4 pg-TEQ / kg bw / day) The upper limit of 95% risk of non-oncogenic risk due to exposure to dioxins, whether inhaled or ingested, is still within acceptable range (ie HI <1);Compared to the TDI (1 μg / kg bw / day) recommended by the US EPA or the TDI (0.8 μg / kg bw / day) recommended by Canada, male and female ethnic groups in various regions of Taiwan are exposed to ingestion The HI of the route is much lower than 1, which means that the upper limit of 95% non-carcinogenic risk due to exposure to (ingested) cadmium is still acceptable (ie HI <1). The booklet on the risk of chemical substance exposure has been compiled with the theme of "dioxin". It contains the latest risk assessment, the current status of domestic policies, the regulation of laws and regulations, administrative measures, and education and publicity. And completed 6 articles on current affairs issues, namely, the " Minamata Convention on Mercury", the " EU's fipronil contamination of eggs", " The EU has identified BPA as the environmental hormone and is listed as a SVHC " Nicotine-like pesticides endanger the bee event "," Perfluorohexylsulfonic acid and its salts (PFHxS) are listed as SVHC "and" Fluoride low-dose exposure during fetal period may present a neurotoxic risk ". This project also completes the revision of the chemical substance knowledge map webpage information, and presents the webpage in the following seven main spindles: 1. Peripheral chemical factories real-time location, 2. Distribution of geographical map information, 3. Environmental pollution regulation information, 4. Domestic and foreign news Information, 5 Information download area, 6 Keyword search, and 7 Online feedback.
Keyword
Chemical substance exposure risk, household chemical safety, human hazard risk
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